What is Injectafer?

Injectafer is a prescription iron replacement medicine used for the treatment of iron deficiency anemia (IDA) in adults and children 1 year of age and older who cannot tolerate iron taken by mouth (oral) or who have not responded well to oral iron or adults who have chronic kidney disease who are not on dialysis (non-dialysis dependent chronic kidney disease)

Injectafer is also used for the treatment of iron deficiency in adults with mild to moderate heart failure to improve the ability to exercise (improve exercise capacity).

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The first and only FDA-approved IV iron to treat ID in appropriate adult patients with HF

50% of people with heart failure have iron deficiency
50% of people with heart failure have iron deficiency

Injectafer is a treatment for iron deficiency in adult patients with mild to moderate heart failure to improve the ability to exercise (improve exercise capacity). This may mean that your healthcare professional doesn't need to start you on oral iron before switching to an IV iron treatment.

Is Injectafer an option for you?

Adult icon
Injectafer is approved to treat adults with:
  • Iron deficiency with mild to moderate heart failure (ask your healthcare professional if this includes you)
  • Injectafer may improve your ability to perform certain physical activities (exercise capacity)
Healthcare professional icon
Your healthcare professional will determine the right dosage of Injectafer for you
  • Each dose of Injectafer is based on your weight and hemoglobin (Hb) levels. Depending on these measures, you may receive 2 doses over a 6-week period
  • You'll receive Injectafer based on their prescribed recommendation
  • Injectafer treatment may be repeated if your healthcare provider decides it is needed

IV=intravenous.

Artwork of a person walking in crosswalk
Artwork of a person walking in crosswalk

Injectafer may help you go the distance

In a clinical study of adults with iron deficiency in heart failure who were treated with Injectafer, a 6-minute walk test was used to measure a person's ability to perform light exercise. This test measures the distance a person can walk in 6 minutes.

People treated with Injectafer also saw significant improvements in their iron levels; ferritin, TSAT, and hemoglobin (Hb).

Injectafer increased the distance study participants could walk by about 82 feet

How far is 82 feet?

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Three quarters of an average grocery store aisle.
Tennis ball icon
About the length of a tennis court.
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A quarter of the width of a city block.*

*Width of city blocks may vary by city.

IRON OPTIONS

Iron supplement icon

Even in healthy patients, when taking oral iron, less than 10% is absorbed by the body.†

IV iron icon

With Injectafer, 100% of the iron goes directly into the bloodstream.

Before you receive Injectafer, tell your healthcare provider about all of your medical conditions

THE WHERE, WHO, AND WHEN OF GETTING INJECTAFER

If your healthcare provider determines Injectafer is right for you, here is some information that may be helpful

The location

Injectafer is given by IV infusion, usually at an infusion center, where a healthcare professional can administer it directly into the bloodstream through a vein.

The providers

Infusion centers are medical facilities equipped and staffed for administering infusions.

The timing

Each Injectafer infusion may take about 15 minutes. Afterward, your healthcare professional will monitor you for about 30 minutes for signs of an allergic reactions or any other side effects.

Tell your healthcare provider right away if you develop any signs or symptoms of allergic reactions during or after treatment with Injectafer.

Your healthcare professional may monitor your serum phosphate levels if you are at risk of low serum phosphate and receive a second course of treatment, or for anyone who receives a second course of treatment within 3 months.

Tell your healthcare provider if you develop any of the following signs or symptoms of low blood phosphate levels during treatment with INJECTAFER:

  • feeling very tired
  • bone or joint pain
  • muscle weakness or pain
  • broken bones

Tips for after your infusion

  • Track your PROGRESS

    by keeping a record of how you're feeling.

  • Call your healthcare professional

    if you're experiencing side effects.

    Injectafer may cause serious side effects.

  • Follow up with your healthcare professional

    to see how well your treatment is working. You may need an additional maintenance dose of Injectafer.

What are the possible side effects of Injectafer?

INJECTAFER may cause serious side effects, including:

  • Allergic reactions. Serious life-threatening allergic reactions that can lead to death have happened in people who receive INJECTAFER and may include the following signs or symptoms:

    • low blood pressure
    • feeling dizzy or lightheaded
    • loss of consciousness
    • trouble breathing
    • swelling
    • fast heartbeat
    • cold or clammy skin
    • feet or hands turn blue
    • itching
    • rash
    • hives
    • wheezing

    Tell your healthcare provider right away if you develop any signs or symptoms of allergic reactions during or after treatment with INJECTAFER.

  • Symptoms of low blood phosphate levels. INJECTAFER may cause low levels of phosphate in your blood that may be serious and can lead to softening of your bones and broken bones (fractures), especially in people who have received multiple INJECTAFER treatments. Your healthcare provider may check your blood phosphate levels before a repeat treatment with INJECTAFER if you are at risk for low blood phosphate levels. If a repeat treatment is needed within 3 months of your last treatment your healthcare provider should check your blood phosphate levels. Tell your healthcare provider if you develop any of the following signs or symptoms of low blood phosphate levels during treatment with INJECTAFER:

    • feeling very tired
    • muscle weakness or pain
    • bone or joint pain
    • broken bones

  • High blood pressure. High blood pressure, sometimes with redness and warmth of the face (facial flushing), dizziness, or nausea, has happened during treatment with INJECTAFER. Your healthcare provider will check your blood pressure and check for any signs and symptoms of high blood pressure after you receive INJECTAFER.

IV=intravenous.